RAF265 alapril D5 maleate tuberculosis

tuberculosis

InChiKey: XZYXCQXTKOYHGK-UHFFFAOYSA-N

Gretler DD

InChi: InChI=1S/C15H20N2O2

PP-121 also blocks tyrosine phosphorylation induced by v-Src in NIH3T3 cells transformed with v-Src(Thr338)

RAF265 alapril D5 maleate tuberculosisCHIR 265 is an orally bioavailable small molecule with potential antineoplastic activity. CHIR 265 binds and inhibits Raf kinases, which may result in a reduction of tumor cell growth and proliferation, and tumor cell death. In addition, this agent inhibits vascular endothelial growth factor receptor type 2 (VEGFR 2), thereby disrupting tumor angiogenesis. Raf kinases are critical enzymes in the Ras Raf MEK ERK signaling pathway and are frequently