VLX1570 - CAS# 1431280-51-1 size:10mg solid 2015 Dec 18:1-12
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VLX1570 - CAS# 1431280-51-1 size:10mg solid 2015 Dec 18:1-12VLX1570, CAS No. 1431280 51 1, is an inhibitor of the 19S proteasome specific deubiquitylating enzymes (DUBs) USP14 and UCHL5, with apoptosis inducing and antineoplastic activities. Upon administration, VLX1570 specifically binds to both USP14 and UCHL5, thereby blocking their deubiquitylating activity. This blocks the ubiquitin proteasome degradation pathway, prevents the degradation of defective proteins, and leads to an accumulation of poly
Store: cgm.lt · Domain: cgm.lt
