DMOG - Prolyl 4-hydroxylase (P4H) Inhibitor. CAS# 89464-63-1 60022 CUDC-101 displays broad antiproliferative activity

CUDC-101 displays broad antiproliferative activity in many human cancer cell types with IC50 of 0

nonspecific cytotoxicity independent of Stat3 activation status

indicating that IOX4 penetrates the blood-brain barrier

and 10 (IC50 > 100 µM)

8(8):e72641

DMOG - Prolyl 4-hydroxylase (P4H) Inhibitor. CAS# 89464-63-1 60022 CUDC-101 displays broad antiproliferative activityDMOG, CAS No. 89464 63 1, is a selective, competitive and cell permeable prolyl 4 hydroxylase (P4H) inhibitor. It inhibits hypoxia inducible factor (HIF ) prolyl hydroxylase (HIF PH). It acts to stabilize HIF 1 expression at normal oxygen tensions in cultured cells, at concentrations between 0. 1 and 1 mM. DMOG acts as a pro angiogenic compound, acting via the HIF 1 system. Product information CAS Number: 89464 63 1 Molecular Weight: 175. 14 Formula: